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Agilent Technologies, Corning, Affymetrix, Bioneer

Agilent Technologies has received US Patent No. 7,331,511, “Biopolymeric array scanners capable of automatic scale factor selection for a plurality of different dyes, and methods for making and using the same.” The patent claims biopolymeric array scanners that are capable of automatically selecting a dye-specific scale factor to employ for different dyes, as well as methods for making and using the scanners. The scanners can be used in both genomics and proteomics applications, the patent states.

Agilent has also received US Patent No. 7,333,907, “System and methods for characterization of chemical arrays for quality control.” Systems, methods and computer-readable media are provided for characterizing a chemical array by generating metrics adapted to: a) identify errors caused by a particular process used in generating the signals on the array; b) generate a quality control report containing at least one of the metrics; and c) output the quality control report.

Corning has received US Patent No. 7,332,328, “Microcolumn-platform based array for high-throughput analysis.” The patent claims a device and methods for performing biological or chemical analysis. The device includes an array of three-dimensional microcolumns projecting away from a support plate. Each microcolumn has a relatively planar, first surface remote from the support plate and an array of multiple, different biological materials may be attached to the first surface. The device, when used in combination with existent microtiter well plates, can improve efficiency of binding assays using microarrays for high-throughput capacity, the patent states.

Affymetrix has received US Patent No. 7,332,378, “Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays.” The patent claims methods of forming arrays of polymers by providing a substrate that has a first layer, including one or more dielectric coatings on a solid support, and a second layer, including a plurality of polymers disposed on the first layer. The patent also provides methods for forming an array of polymers on a substrate using light-directed synthesis.

Bioneer of Daejon, Korea, has received US Patent No. 7,333,274, “Process of quality examining for microarray of biological material.” The patent describes a process of examining a microarray by: a) mixing probes and a compound which emits light or heat and does not react with the probes; b) arraying the mixture obtained on a substrate; and c) measuring the light or heat emitted by the scanning of each spot of the microarray mixture.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.