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Agilent Technologies : Jul 1, 2008

Agilent Technologies last week launched DNA Analytics 4.0, a software package for visually exploring, detecting, and analyzing patterns in microarray data.
Agilent said that DNA Analytics 4.0 offers the ability to analyze more than 100 samples per experiment as well as a free genomic browser and copy number variation analysis capability.
The previous version of DNA Analytics included chromatin immunoprecipitation-on-chip, array-based comparative genomic hybridization, and gene expression analytics capabilities, Agilent said.

The company also has updated its eArray online design tool for creating custom microarrays by expanding the CGH probe database from 8.4 million to more than 24.5 million probes.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.