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Agilent Technologies: Dec 14, 2005

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Agilent Technologies of Palo Alto, Calif., has received US Patent No. 6,974,703, "Electro-optical devices and methods for hybridization and detection." The patent claims an apparatus and method for detecting the presence of a target molecule. The apparatus comprises a probe labeled with a transition metal-ligand complex for hybridizing with the target to form an initial complex, metal ions for doping the initial complex and forming a final complex, and means to produce a detectable signal indicating the presence of the target. The method comprises hybridizing a probe having an attached label to a target to produce an initial complex, adding metal ions to the initial complex to make a final complex, and applying a potential to the final complex to produce a measurable signal.

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