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Affymetrix, Spectral Genomics, Genetix, SuperArray Bioscience


Affymetrix this week launched version 2.0 of its GeneChip Mapping 10K Array and the GeneChip Mapping 100K set. Both products utilize the same assay developed for the earlier GeneChip Mapping 10K Array and require one universal primer and a simple protocol, the company said. Pricing details were not disclosed.

Spectral Genomics of Houston this week introduced the Constitutional Chip BAC Clone Microarray for comparative genomic hybridization applications. The Constitutional array, containing 464 BAC clones associated with “constitutional” analysis of 41 known genetic syndromes and telomere abnormalities, is capable of detecting single-copy-number changes, the company said. The chip also includes spots representing negative controls, calibration controls for standardization of detection, and clones not likely to be affected by genetic defects that form the baseline for detection. Among the clones are those believed to be associated with common pre-natal and post-natal analysis of genetic defects based on established practices including, trisomy 21, trisomy 18, Wolf Hirshorn Syndrome, DiGeorge Syndrome, and Cri du Chat Syndrome.

Genetix announced a new blue laser option for its aQuire dual-laser scanner for use in the detection of GFP, fluorescein, and other fluorophores and for application in imaging DNA, protein, cell, and tissue microarrays. The laser is available for $22,000, the company said.

SuperArray Bioscience of Frederick, Md., this week launched two new arrays in its Oligo GEArray line of pathway specific DNA microarrays with content specific to human hematology and cancer.

The products use chemiluminescence detection and a one-tube labeling method and can be processed using basic molecular biology lab equipment. The arrays are constructed of customizable, 60-mer oligonucleotide probes, and sell for $100 each.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.