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Affymetrix, Plasmodium/Anopheles Genome GeneChip Array, Illumina, Sentrix BeadChip, VizX Labs, GeneSifter.Net, Ingenuity, and Pathways Analysis

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Affymetrix last week introduced the Plasmodium/Anopheles Genome GeneChip Array, a catalogue array that contains DNA probes for the genomes of the malaria parasite, Plasmodium falciparum, and the host mosquito, Anopheles gambiae.

The array was developed in collaboration with the Malaria Research Institute of the Bloomberg School of Public Health at Johns Hopkins University. Through a program sponsored by NIAID/NIH, the new array will be available to qualified, registered users of the Malaria Research and Reference Reagent Resource Center located in Manassas, Va. Pricing details were not disclosed.


San Diego-based Illumina last week announced that it is offering two new human gene-expression products on its Sentrix BeadChip platform (see article, page 1). The company is offering a whole-human genome chip that can sample six separate samples on one array, with six discrete areas containing DNA probes for interrogating approximately 48,000 transcripts from the estimated 30,000 genes in the human genome.The second BeadChip product analyzes eight samples in parallel against the roughly 22,000 genes represented in the consensus RefSeq database. Illumina uses a bead scheme for its instrumentation, with each bead holding 50-base-long, gene-specific DNA probes. Pricing details were not disclosed.


Seattle, Wash.-based VizX Labs last week announced the release of the first of four planned 2004 upgrades to Seattle, Wash.-based VizX Labs last week announced the release of the first of four planned 2004 upgrades to GeneSifter.Net, the company’s web-based microarray data analysis software. Pricing details were not provided. The product includes new features specific for Affymetrix platform users including a probe-level analysis method for multiple arrays, a Gene Ontology report using Z-score statistics to target particular families of genes, MIAME-compliant protocols, and statistical analysis techniques. , the company’s web-based microarray data analysis software. Pricing details were not provided. The productincludes new features specific for Affymetrix platform users including a probe-level analysis method for multiple arrays, a Gene Ontology report using Z-score statistics to target particular families of genes, MIAME-compliant protocols, and statistical analysis techniques.


Mountain View, Calif.-based Ingenuity introduced an upgrade to its Pathways Analysis software, which generates possible multiple biological networks by associated functional analysis using specific gene or protein datasets in conjunction with Ingenuity’s database. The product contains new gene and protein dataset mapping, including two new Affymetrix arrays, the company said.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.