Affymetrix, Merck, California Institute of Technology, Imaging Research, Able Signal | GenomeWeb

Affymetrix earned US Patent No. 6,566,515, “Photocleavable protecting groups and methods for their use.” The patent covers novel compounds for use as linking groups in chemical synthesis, preferably in the solid-phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups that may be removed by photolysis to unmask a reactive group.

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