Affymetrix, Incyte, The University of Kentucky Research Foundation, PE Corporation/Applera | GenomeWeb

Affymetrix has received US Patent Number 6,420,169, “Apparatus for forming polynucleotides or polypeptides.” The patent covers a method for in situ synthesis of oligonucleodides, first by irradiating a predefined region of the substrate to deprotect the substrate. A nucleotide is then added to the substrate in the irradiated region, and is coupled to it. These steps are repeated in order to create an array of oligonucleotides.


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