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Affymetrix, Corimbia, Open Biosystems

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Affymetrix is now offering customers early access to a new product called CustomSeq for resequencing up to 30 kb of unique sequence (60 kb if counting both strands). The tiling strategy is different from its HuSNP probe arrays, according to the company. Affymetrix will make further details available at a later date.

Corimbia has released its Probe Profiler software for signal quantification and data quality assessment of data obtained from Affymetrix arrays. According to Corimbia, the software analyzes data across an experiment rather than one scan at a time, and is able to determine data quality problems associated with chip quality, RNA quality, and scanner problems quickly.

Open Biosystems of Huntsville, Ala., is offering cDNA and EST clones. The company said it is going to distribute the DOE/NCI’s IMAGE cDNA clone selection but will initially focus on supplying full length cDNA subsets called the Mammalian Gene Collection. MGC contains over 11,000 human and 8,500 mouse full length sequenced cDNA clones. Moreover, Open Biosystems will offer the University of Iowa’s Rat Non Redundant EST Collection and other collections, both individually and as complete sets. It is also building pathway-specific subsets for printing microarrays or expressing proteins. Furthermore, the company offers two collections of mapped BAC clones, created by the NCI and the Human BAC Consortium, that cover the human genome. BAC DNA from these collections could be used to print arrays for comparative genomic hybridization, according to the company.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.