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Affymetrix, Cellomics

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Affymetrix said this week that it will launch its new scanner, the GeneChip Scanner 3000, at the Lab Automation 2003 convention in Palm Springs, Calif., Feb. 2-4 (see page 1).

Pittsburg-based Cellomics rolled out three software modules for its ArrayScan High Content Screening Reader and the vHCS Discovery ToolBox this week. The Molecular Translocation module allows the study of multiple signal transduction pathways involving biomolecules such as transcription factors and kinases within a single experiment. Up to five individual translocation events can be measured in each cell and reporting features indicate population characteristics and correlations between multiple targets.The Micronucleus application is a multi-channel module that enables detection of genotoxicity by examining the frequency of micronucleus formation in mononucleate or binucleate cells. The Cell Cycle application is also a multi-channel software that is used to measure the cell-cycle phase of individual cells within a population by measuring DNA content and correlating this with the activity of multiple other cell cycle-associated proteins in each cell. Then, the application uses population analysis and classification to determine the distribution of phases for individual cells.

The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.