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Affymetrix, Baylor, OGT, BioSolution, Integromics

Affymetrix Licenses Array IP to Baylor for CLIA-based CGH Services
Baylor College of Medicine has licensed a number of patents from Affymetrix to perform certain microarray services in Clinical Laboratory Improvement Amendments environments, the groups said this week.
Under the terms of the deal, scientists at Baylor’s Department of Molecular and Human Genetics will have non-exclusive rights to use Affy’s patents for comparative genomics hybridization microarray services.
Arthur Beaudet, chair of Baylor’s DMHG, said the scientists will use the technology “to identify specific genetic abnormalities in many children that have developmental disabilities with previously unknown causes.”
The DMHG conducts research in a wide variety of fields, including functional genomics, sequencing, human and mammal genome studies, and numerous diseases.
Financial details or the duration of the agreement were not disclosed.

OGT to Provide Arrays for CHAVI-Funded HIV Vaccine Research Project
Oxford Gene Technology has been selected to design and manufacture microarrays for the Innate Discovery Team, a project funded through the Center for HIV-AIDS Vaccine Immunology that is developing vaccines for HIV.

Specifically, OGT will design and develop an optimized oligonucleotide microarray to study genes involved in the cellular immune response in early stage HIV-infected patients. The microarrays will be printed using the OGT inkjet in situ synthesis platform. OGT said that the study will also use its Multi Sample Array format to enable the parallel analysis of multiple samples.

Financial details were not discussed.           

BioSolution to Market Integromics' Microarray Software in France
Spanish software developer Integromics said last week that BioSolution, a Paris-based biotech consulting company, will market its products in France.
Integromics’ software focuses on microarray management, including data analysis and data mining.
Financial terms of the deal were not disclosed.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.