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Affymetrix, Applied Biosystems, Fuji Photo Film


Affymetrix has released new versions of its GeneChip E. coli Genome 2.0 Array and Yeast Genome 2.0 Array, offering updated genomic content. The E. coli array contains three new strains of E. coli and probe sets to detect more than 20,000 transcripts. The array also detects transcripts involved in antibiotic resistance. The yeast array enables researchers to analyze the genomes of Saccharomyces cerevisiae and Schizosaccharomyces pombe on the same chip. The array contains over 10,000 transcripts, which is nearly twice the content available on the previous generation array.

Applied Biosystems has launched the 9800 Fast PCR System, which provides PCR results in a standard 96-well plate in approximately 25 minutes. The system includes the 9800 Fast Thermal Cycler, the GeneAmp Fast PCR Master Mix, and the 96-well Fast Thermal Cycling Plate. The company plans to unveil the system at the upcoming American Society of Human Genetics Annual Meeting in Toronto. The introduction follows last week’s launch of ABI’s 7900HT Fast Real-Time PCR System.

Fuji Photo Film has launched the QuickGene 800 DNA/RNA isolation system. According to the firm, the tabletop system can deliver a DNA whole-blood sample in as little as six minutes.

The Scan

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.

Breast Cancer Risk Gene Candidates Found by Multi-Ancestry Low-Frequency Variant Analysis

Researchers narrowed in on new and known risk gene candidates with variant profiles for almost 83,500 individuals with breast cancer and 59,199 unaffected controls in Genome Medicine.

Health-Related Quality of Life Gets Boost After Microbiome-Based Treatment for Recurrent C. Diff

A secondary analysis of Phase 3 clinical trial data in JAMA Network Open suggests an investigational oral microbiome-based drug may lead to enhanced quality of life measures.

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.