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Affymetrix: Dec 10, 2003

Premium

Affymetrix is offering its mouse 430 2.0 Array, a single microarray covering 39,000 transcripts, which were previously available as a multiple array set. It has 45,000 probe sets and 981,228 distinct oligonucleotide features covering over 39,000 transcripts and variants, including over 34,000 well-substantiated mouse genes. The product also includes eleven pairs of oligonucleotide probes used to measure the level of transcription of each sequence. The mouse GeneChip requires 200 microliters of hybridization volume. The sequences used for the probes were derived from GenBank, dbEST, and RefSeq. The array requires the company’s GeneChip 3000 scanner, enabled for high-resolution scanning, and the GeneChip operating system v1.1.1. The mouse chip is available for purchase in sets of 2, 6, or 30 arrays.

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.