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3m Innovative Properties Company, Genicon Sciences, Large Scale Proteomics, Agilent Technologies, The Center for the Application of Molecular Biology to International Agriculture, Rosetta Inpharmatics


3m Innovative Properties Company has received US Patent No. 6,714,675, Autogrid analysis. The patent describes a method and apparatus to identify the positions of elements of a grid, as well as the orientation of the grid. The method can be used for multi-sided grids, and the addresses can be used for analytical procedures that are directed to individual grid elements.

Genicon Sciences (which was acquired by Invitrogen in July 2003), has obtained US Patent No. 6, 714, 299, “Use of light scattering particles in design, manufacture, and quality control of small volume instruments, devices, and processes.” The patent describes Genicon’s Resonance Light Scattering technology, which incolves the use of these light scattering particles in design, manufacture and quality control of microscale devices, as well as the analysis of the substrate for these particles. See BAN 10-19-01.

Large Scale Proteomics, a subsidiary of Large Scale Biology, has received US Patent No. 6, 713,309, “Micro-arrays and their manufacture.” These are prepared using a separate fiber for each compound, and are bundled to form a thin microarray glued to a backing.

Agilent Technologies has received US Patent No. 6,713,262, “Methods and compositions for high throughput identification of protein/nucleic acid binding pairs.” The patent describes methods to identify protein-nucleic acid binding pairs in a high-throughput manner, using a nucleic acid probe array. The array is hybridized to target nucleic acids, then a protein population is added to it. The target nucleic acid-protein complexes are then detected. The patent also describes systems and kits for these arrays.

The Center for the Application of Molecular Biology to International Agriculture, of Black Mountain, Australia, has received US Patent No. 6,713,258, “Methods for genotyping by hybridization analysis.” The invention involves methods for determining an organism’s genotype and establishing the relationship between organisms in a species using hybridization analysis. It includes addressable arrays with panels of nucleic acid molecules to distinguish between different nucleic acid samples. The products of this panel are hybridized with labeled nucleuc acids to determine the genotype of an organism.

Rosetta Inpharmatics, (now a Merck subsidiary) has received US Patent No. 6,713,257,”Gene discovery using microarrays.” The patent relates to methods and systems to identify and characterize genes using microarrays. In particular it involves ways to map gene expression to the structure of the genome.


The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more