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Århus University, Eppendorf Array Technology, Gene Logic, University of Pittsburgh

Århus University of Århus, Denmark, has received European Patent No. 1875234, “Biosurface structure array.” The patent claims an array for testing different microenvironments for cultivation of cells or organisms. The array contains a number of testing areas on a metal surface. The testing areas may contain biomolecules including antibodies, antigens, glycoproteins, or DNA, the patent states. Users can use the array to compare the frequency of attachment of cells or organisms to any one tester area of the biosurface structure array; to compare the spread of cells or organisms on any one tester area of the array; or to compare differentiation of cells or organisms attached to any one tester area of the array.

Eppendorf Array Technology of Namur, Belgium, has received US Patent No. 7,321,829,Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips.” The patent describes a method for the identification or the quantification of a target compound obtained from a biological sample. The method includes the steps of: a) contacting the target compound with a capture molecule in order to allow a specific binding between the two; b) fixing the capture molecule on the surface of a solid support containing an array with at least 20 discrete regions; c) performing a reaction leading to a precipitate formed at the location of the binding, determining the possible presence of precipitates in the separate regions; and d) correlating the presence of the precipitates at the discrete regions with the identification and/or a quantification of the target compound.


Gene Logic of Gaithersburg, Md., and the University of Pittsburgh have received US Patent No. 7,321,830, “Identifying drugs for and diagnosis of benign prostatic hyperplasia using gene expression profiles.”The patent claims a computer system and database for elucidating changes in gene expression in prostate tissue isolated from patients exhibiting different clinical states of prostate hyperplasia as compared to normal prostate tissue, as well as the identification of individual genes that are differentially expressed in diseased prostate tissue.

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