Skip to main content
Premium Trial:

Request an Annual Quote

Yale Sequences Genome of Symbiotic Bacterium Sodalis glossinidius

NEW YORK, Dec. 20 (GenomeWeb News) - Researchers at Yale School of Medicine have sequenced the genome of the symbiotic bacterium Sodalis glossinidius, the university announced last week.

 

Sodalis is a maternally transmitted endosymbiont of tsetse flies, and is one of three kinds of bacteria that help the tsetse fly feed off the host's blood. It is related to human bacterial pathogens like Escherichia coli, Salmonella, and Yersinia.

 

The Yale researchers found that Sodalis had many of the same features of pathogenic bacteria, although it is a beneficial organism that does not harm its tsetse fly host. Serap Aksoy, professor in the Department of Epidemiology and Public Health at Yale School of Medicine, said in a statement that this finding "has changed our view of host pathogen characteristics." 

 

At around 4 million base pairs and approximately 2,400 protein-coding sequences, the Sodalis genome has a physical structure and size similar to that of free-living bacteria, the researchers said.

 

Scientists grew Sodalis in vitro in the laboratory and genetically modified it before inserting into the fly.

 

The results were published online on Dec. 15 in Genome Research and will appear in the print publication in February 2006.

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more