NEW YORK, July 31-Xeotron has developed a new way to make peptide microchips using digital photolithography, the company said.
Using a silicon-based microfluidics chip and a photoreactive process, Xeotron researchers were able to generate between 2,000 and 4,000 peptide sequences on a 1.5-square-cm chip.
Company researchers verified that the microchip sequences showed specific antibody binding, suggesting that the technique could prove useful in developing commercially or clinically useful peptide chips.
According to the authors, this method is significantly cheaper and more efficient than the photomasking approach used by other peptide chip developers.
The technique, the result of a collaboration with scientists at the University of Houston and the University of Michigan, appears in a journal article in the July 22 edition of Nature Biotechnology.
Xeotron is a privately held photochemical and microfluidics company based in Houston.