A Whole New System


Founded in 2000 by well-known scientists who defected from their academic posts at the nearby University of Washington, the Institute for Systems Biology laid the groundwork for academic and for-profit organizations alike to buy into the nascent concept of large-scale biology. And buy in they did: institutes for high-throughput, systems-level science have flourished around the world. "I think as a field we have done very, very well given that it has been less than 10 years," says Alan Aderem, who co-founded ISB with Ruedi Aebersold and Lee Hood in 2000.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.

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