Spend half an hour talking to Cold Spring Harbor Laboratory’s President Bruce Stillman about the government funding crunch, and you too may feel like taking a long walk off a short pier. “If you’re in the trenches of science now, it is very, very difficult and there’s a lot of despair,” he says.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.