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Where Were You When Gen G Was Generated?

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The 16 up-and-comers featured in this month’s cover story were born between 1967 and 1973. Here’s some trivia to put the dates in perspective.

1967

• Laws forbidding the teaching of the theory of evolution in Tennessee schools are repealed

• Craig Venter turns 21 as a corpsman in Da Nang, Vietnam

1968

• James Watson publishes The Double Helix

• Fred Sanger uses radioactive phosphorous as a tracer to chromatographically decipher a 120-base-long RNA sequence

• 29-year-old Lee Hood, who already holds an MD from Johns Hopkins, completes his PhD at Cal Tech

1969

• Defense Advanced Research Projects Agency goes online, connecting four major US universities. Designed for research, education, and government organizations, it provides a communications network linking the country in the event that a military attack destroys conventional communications systems

1970

• Hamilton Smith and Daniel Nathans isolate the first restriction enzyme (work for which Smith wins the Nobel prize in 1978)

• Howard Temin and David Baltimore independently discover reverse transcriptase enzymes

• John Gurdon uses nuclear transplantation to clone a frog — first cloning of a vertebrate

• IBM introduces the floppy disk

• Hoffman-La Roche invents the liquid crystal display

1971

• Nixon signs National Cancer Act, earmarking $1.6 billion for cancer research

• 518 protein sequences are listed in the Atlas of Protein Sequence & Structure, Volume V

• GE applies for patent on bacteria that digests oil, opening door for patenting of living organisms

• “Computer Space” is first video arcade game ever released

• Texas Instruments releases the first easily portable electronic calculator

• Intel introduces the 4004 Microprocessor

1972

•Electronic mail is born

• Magnavox launches “Odyssey,” the first home video game system

1973

• Transmission Control Protocol/ Internet Protocol is designed. Ten years later it becomes the standard for communicating between computers over the Internet

1974

• Eric Lander (third from left, with his math team) is class valedictorian at Stuyvesant High School in New York

The Scan

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.

New Insights Into TP53-Driven Cancer

Researchers examine in Nature how TP53 mutations arise and spark tumor development.

Mapping Single-Cell Genomic, Transcriptomic Landscapes of Colorectal Cancer

In Genome Medicine, researchers present a map of single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer.

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.