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My television has been acting up lately. It's sporadic — wavy lines come and go at their leisure, for no apparent reason. They do tend to crop up at inconvenient times — during a key play in a basketball game or right as somebody is about to confess on Law & Order. And sure, when I'm playing Wii, the little tennis players run off the side of the screen, causing me to miss my shot. But is it time to get a new one? Though it is old and far from a fancy, high-definition flat screen, my television still works.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.