A.The biggest hurdle is the expense for performing well-designed experiments that will enable the investigator to apply mathematical modeling approaches to the resulting data. Both gene expression microarray and proteomics experiments still are expensive, especially if you add on 3-4 replicates for each data point and do the reiterative sampling of time or dose (8-10 different data points) that is required for systems biology.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.