This Week in NEJM


In NEJM this week, researchers in Europe and Canada report a study on the use of semuloparin for thromboprophylaxis in cancer patients receiving chemotherapy. The team randomly assigned 1,608 patients with metastatic or locally advanced solid tumors to receive either subcutaneous semuloparin or placebo in addition to chemotherapy. They found that venous thromboembolism occurred in 1.2 percent of patients who had received semuloparin compared with 3.4 percent in the placebo group.

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The London School of Economics' Daniele Fanelli argues at the Proceedings of the National Academy of Sciences that the reproducibility crisis in science isn't as dire as some say.

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