This Week in NEJM

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In NEJM this week, an international team of researchers reports a study of RAS mutations in patients with cutaneous squamous cell carcinoma who were treated with BRAF inhibitors. The team analyzed oncogenic mutations in the lesions of 21 patients treated with BRAF inhibitor vemurafenib. Out of the 21, 13 had RAS mutations, the team found, as did eight out of 14 samples in a validation set.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.