This Week in NEJM


In NEJM this week, researchers in Michigan, North Carolina, and Arizona identify germline mutations in HOXB13 that may increase a person's risk for prostate cancer. Family history has been shown to be a significant risk factor for prostate cancer, but its molecular basis has not yet been properly understood, the researchers write. In this study, the team screened more than 200 genes on chromosome 17q21-22 from germline DNA of 94 patients with familial prostate cancer.

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The ancestors of the Arizona bark scorpion and other scorpions and spiders underwent whole-genome duplication, KJZZ reports.

A cryptographic approach could help researchers keep genomic data private while researchers analyze it, Scientific American reports.

Andy Page, the former president of 23andMe, has joined a diabetes-management startup, according to CNBC.

In Cell this week: regulatory changes in pancreatic cancer, metabolic shifts in Alzheimer's disease, and more.