In the Journal of the National Cancer Institute, researchers from the Vanderbilt University School of Medicine report on the oncogenic potential of EPHA3 mutations in lung cancer. Using immunoprecipitation, western blotting, and kinase assays, the team investigated the activity and signaling of mutant EPHA3 receptors, and generated a mutation-associated gene signature to test in human lung cancer tissue microarrays and xenograft models.

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 Senator Lamar Alexander (R-Tenn.), who chairs the Senate health committee, will be retiring at the end of his term, Stat News reports.

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

The Wall Street Journal reports on the US Centers for Disease Control and Prevention's use of genetic approaches to study foodborne illnesses.

In PNAS this week: immune cell profiling of wild baboons by social status, metabolomics profiling of esophageal tumors, and more.