The Women’s Health Initiative study of estrogen therapy in women with hysterectomies was stopped early in 2004 due to an increased risk of stroke, and in a new study published this week in JAMA, researchers from the WHI report on the long-term health outcomes of the women in that study after stopping therapy. The women in the double-blind, placebo-controlled, randomized clinical trial received either conjugated equine estrogens or placebo for a median of 5.9 years, and then were followed for a mean of 10.7 years.