In JAMA this week, researchers at the University of Texas MD Anderson Cancer Center and the University of Chicago report on the effects of brachytherapy versus whole-breast irradiation and subsequent mastectomy on the survival of older women with invasive breast cancer. The team retrospectively studied 92,735 women aged 67 and older with invasive breast cancer, 6,952 of whom were treated with brachytherapy after lumpectomy and 85 of whom were treated with whole-breast irradiation.