This Week in JAMA


In JAMA this week, Alberts et al. examine the effect of adding cetuximab to oxaliplatin, fluorouracil, and leucovorin on the survival of patients with resected stage III colon cancer. The team randomly assigned 2,686 patients to receive the standard leucovorin, fluorouracil, and oxaliplatin — or FOLFOX — adjuvant therapy either with or without cetuximab. After a median follow-up of 28 months, the team found no benefit of adding cetuximab.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.