This Week in JAMA


In JAMA this week, Alberts et al. examine the effect of adding cetuximab to oxaliplatin, fluorouracil, and leucovorin on the survival of patients with resected stage III colon cancer. The team randomly assigned 2,686 patients to receive the standard leucovorin, fluorouracil, and oxaliplatin — or FOLFOX — adjuvant therapy either with or without cetuximab. After a median follow-up of 28 months, the team found no benefit of adding cetuximab.

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Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.

Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.

Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.

In Science this week: gut microbiome influences liver cancer growth, spread; and more.