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This Week in JAMA: Sep 28, 2011


In JAMA this week, researchers from Austria explore the gender-specific prevalence of adenomas and advanced adenomas in colorectal cancer patients undergoing colonoscopy screening. The team analyzed data from 44,350 participants of a national screening colonoscopy program in Austria from 2007 to 2010. Adenomas were found in 19.7 percent of colonoscopy participants, and being male was significantly associated with a higher prevalence of adenomas, the authors write.

Also in JAMA this week, the journal's Rebecca Voelker reports on new cancer care accreditation standards for hospital cancer programs that call for approaches to help patients and their families deal with the myriad and complex diagnoses and treatment options, and to better coordinate care among different medical professionals. The American College of Surgeon's Commission on Cancer developed the new standards with the support of four cancer advocacy groups, including the American Cancer Society. To be accredited by the CoC, hospitals will have to provide, among other things, screening to help patients deal with mental distress, palliative care, and genetic services, Voelker says.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.