This Week in JAMA


In JAMA this week, a team of researchers in Italy presents findings from a study of the effects of triptorelin — a gonadotropin-releasing hormone analog — on the occurrence of chemotherapy-induced early menopause in women with breast cancer. To determine if triptorelin's temporary ovarian suppression effect changed the rate of early menopause during chemotherapy, the team studied 281 premenopausal breast cancer patients and randomly assigned them to receive either chemotherapy alone or with triptorelin.

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Researchers describe a way to share data while keeping it secure, Agence France Presse reports.

In Science this week: genetic mutations typically associated with esophageal cancer are common in older, healthy individuals, and more.

India's Council of Scientific and Industrial Research has a new director-general, according to ScienceInsider.

A new study links more than a hundred genes to autism spectrum disorder, Discover's D-brief blog reports.