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In Clinical Cancer Research, researchers in the US and Europe elucidated the biological role of transcription factor Sp1 in multiple myeloma. Sp1 controls a number of cellular processes, the researchers write. For this study, they investigated functional Sp1 activity in multiple myeloma cell lines, and found that there is high Sp1 activity in the cancer cells and that it is further induced by adhesion to bone marrow stromal cells.

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St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.