In Clinical Cancer Research, researchers in the US and Europe elucidated the biological role of transcription factor Sp1 in multiple myeloma. Sp1 controls a number of cellular processes, the researchers write. For this study, they investigated functional Sp1 activity in multiple myeloma cell lines, and found that there is high Sp1 activity in the cancer cells and that it is further induced by adhesion to bone marrow stromal cells.

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In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.