In Clinical Cancer Research this week, researchers at the University of Michigan Comprehensive Cancer Center report that upregulated JAG1 in adrenocortical carcinoma enhances proliferation of cancer cells in adrenocortical Carcinoma. The team found that JAG1 expression is upregulated in most adrenocortical carcinoma cell lines, and that it enhances cell proliferation through the activation of canonical Notch signaling.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.