This Week in Cancer Discovery


Researchers led by the Dana-Farber Cancer Institute's William Hahn report in Cancer Discovery that the gene CRKL is amplified and over-expressed in non-small cell lung cancers with 22q11.21 amplifications. CRKL. Further, the "over expression of CRKL induces cell transformation and resistance to epidermal growth factor receptor inhibitor treatment and [suggests] that therapeutic interventions targeting CRKL may confer a clinical benefit in a defined subset of NSCLCs," the authors write.

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A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.

A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.