This Week in Cancer Discovery | GenomeWeb

This Week in Cancer Discovery

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In Cancer Discovery this week, researchers in Maryland and Massachusetts say that HIF1-alpha could function as a 14q kidney cancer suppressor gene. Kidney cancers often delete chromosomes 3p and 14q, which contain tumor suppressor genes, the authors write. For this study, the team identified focal, homozygous deletions of the HIF1-alpha locus on chromosome 14q in clear renal carcinoma cell lines — wild-type HIF1-alpha suppresses renal carcinoma growth, but the altered loci don't.

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In PLOS this week: a sequencing-based screen of Lyme disease-causing pathogen, the range of animals bitten by Anopheles darling mosquitoes in Peru, and more.

An NC State researcher is exploring the use of CRISPR-Cas3 as an anti-microbial, Gizmodo reports.

The Earth BioGenome Project plans to sequence all life on Earth, according to ScienceInsider.

For those who are concerned about Trump administration actions related to science, a new column in Scientific American has suggestions for ways to fight back.