This Week in Cancer Discovery

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In Cancer Discovery this week, researchers in Maryland and Massachusetts say that HIF1-alpha could function as a 14q kidney cancer suppressor gene. Kidney cancers often delete chromosomes 3p and 14q, which contain tumor suppressor genes, the authors write. For this study, the team identified focal, homozygous deletions of the HIF1-alpha locus on chromosome 14q in clear renal carcinoma cell lines — wild-type HIF1-alpha suppresses renal carcinoma growth, but the altered loci don't.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.