This Week in Cancer Discovery | GenomeWeb

This Week in Cancer Discovery

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In the newest issue of Cancer Discovery, researchers in the US and Spain report on the HIF-1α hypoxia response in tumor-infiltrating T lymphocytes. They found that CD8 and CD4 tumor-infiltrating T lymphocytes from colon carcinomas, melanomas, and spontaneous breast adenocarcinomas transplanted into mice are CD137-positive and that the expression of CD137 on activated T lymphocytes is enhanced by hypoxia and the prolyl-hydroxylase inhibitor dimethyloxalylglycine.

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In PLOS this week: genetic factors associated with facial features, a new mutation that makes individuals more prone to Brugada syndrome, and more.

Nutrigenomic companies offer gene-based diet advice, the Wall Street Journal reports.

Researchers have found a new kind of virus — one that starts out broken up into five parts.

Nature News explores the president's "science legacy."