This Week in Cancer Discovery

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Researchers from the Institute of Cancer Research in London report in Cancer Discovery that functional genetic profiling of breast cancer allows the cancer to be classified into subgroups that are different from established subtypes. Using an siRNA library targeting human protein kinases in breast tumor cell lines, the researchers confirm that ERBB2 and PIK3CA are candidate targets for breast cancer therapeutics.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.