This Week in Cancer Cell

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In Cancer Cell this week, a team of US researchers report on targeting non-classic oncogenes for the treatment of T-cell acute lymphoblastic leukemia. PI3K/Akt activation is common in T-ALL, the team says. In this study, they report that the absence of PTEN phosphatase tumor suppressor function can lead to the PI3K-gamma or PI3K-delta isoforms supporting leukemogenesis alone, even though suppression of both isoforms was required to suppress tumor formation.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.