This Week in Cancer Cell | GenomeWeb

This Week in Cancer Cell


In Cancer Cell this week, researchers in France, Spain, and the Netherlands present a mouse model of small-cell lung cancer that they say shows a functional role for tumor cell heterogeneity. SCLC tumors are often composed of neuroendocrine and mesenchymal cells, and mesenchymal cells can endow neuroendocrine cells with metastatic capacity, the authors write. Oncoprotein RasV12 can make neuroendocrine cells transition to a mesenchymal phenotype, facilitating metastasis.

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Pacific Biosciences is hosting a competition in which researchers are vying to win free sequencing for an organism with the most interesting genome.

An opinion piece appearing in Newsday likens familial DNA searches to stop-and-frisk policies.

The San people of Africa have drawn up a code of conduct for researchers, according to the Conversation.

In Nature this week: genotypes linked to hip osteoarthritis, and more.