In the British Journal of Cancer this week, researchers in California and China say that downregulation of SOX2 in cancer stem cells suppresses the growth and metastasis of lung cancer. The researchers show that D121-SP cancer cells contain cancer stem cell characteristics as demonstrated by an upregulation of transcription factors SOX2 and Oct 4. More importantly, the migration of D121-SP was decreased and apoptosis was upregulated after a knockdown of SOX2 in the cells, the authors write.

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Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.

Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.

In Science this week: research regulation and reporting requirement reform, and more.

With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.