This Week in the British Journal of Cancer | GenomeWeb

In the British Journal of Cancer this week, researchers in California and China say that downregulation of SOX2 in cancer stem cells suppresses the growth and metastasis of lung cancer. The researchers show that D121-SP cancer cells contain cancer stem cell characteristics as demonstrated by an upregulation of transcription factors SOX2 and Oct 4. More importantly, the migration of D121-SP was decreased and apoptosis was upregulated after a knockdown of SOX2 in the cells, the authors write.

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In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.