In the British Journal of Cancer, researchers from South Korea present a dose-escalation study of the drug irinotecan for patients with advanced gastric cancer, and determine the drug's effect on the UGT1A1 genotype. The team administered increasing doses of irinotecan to 43 patients and sequenced DNA isolate from their peripheral blood to determine their UGT1A1 genotypes. The overall response rate was 9.3 percent, and the disease control rate was 62.8 percent.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.