In the British Journal of Cancer this week, researchers from Washington University School of Medicine report the role of sigma-2 ligands in cancer cell death. The team treated EMT-6 mouse breast cancer cells and MDA-MB-435 human melanoma cells with sigma-2 ligands and found that three of these ligands induced DNA fragmentation, activated caspase-3, and caused PARP-1 cleavage.

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In Science this week: International Wheat Genome Sequencing Consortium publishes the bread wheat cultivar Chinese Spring reference genome, and more.

At his FDA Law Blog, Jeffrey Gibbs discusses FDA's technical assistance for the draft Diagnostic Accuracy and Innovation Act.

The New York Times reports that genetic testing has uncovered unfaithful penguins at a Utah aquarium.

Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.