In the British Journal of Cancer this week, researchers in Belgium assess the clinicopathological significance of IDO1 expression in colorectal cancer. Because it modulates T-cell response to infection, IDO1 may be co-opted by carcinomas to create an immunosuppressive state, the authors write. In this study, the team investigated IDO1 expression in three colon cancer cell lines, and found that higher IDO1 expression at the tumor invasion site was an adverse prognostic marker.

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Researchers suggest that genetic variations could influence the side effects people experience when using synthetic cannabinoids, the International Business Times reports.

An analysis has examined the makeup of researchers on Twitter and what they share, Nature News reports.

At Stat News, Jim Kozubek argues that the Broad Institute is pushing the boundary of what a nonprofit is.

In PNAS this week: gut microbes may affect honeybee weight, phenotype and gene expression changes in DiGeorge syndrome, and more.