This Week in BMC Cancer | GenomeWeb

This Week in BMC Cancer

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In BMC Cancer this week, researchers in Greece report on the role of thymidylate synthetase, or TYMS, in non-small-cell lung cancer. The team examined the mRNA expression of DNA repair and replication genes BRCA1, ERCC1, RRM1, and TYMS in 276 NSCLC samples and found that expression of all four genes was increased in tumors compared to matched normal lung parenchyma. In particular, the researchers found that aberrant intratumoral TYMS expression predicted shorter progression-free survival.

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In PNAS this week: mutations linked to nasopharyngeal carcinoma, salivary proteins common among oral squamous cell carcinoma patients, and more.

At Wired, a science journalist discusses her decision not to undergo BRCA testing.

The Japan Times says regulations are needed to oversee human genome-editing research.

In PLOS this week: molecular surveillance of S. Typhi, genome-wide association study of attention in children, and more.