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This Week in BMC Cancer : Jul 2, 2012


A team led by scientists at the Korea Research Institute of Bioscience and Biotechnology in Daejeon, South Korea, this week presents in BMC Cancer a 3D structure for GIG47 — a candidate oncogene implicated in multiple human cancers — which they determined using multidimensional heteronuclear NMR methods. The authors say the structure they report could facilitate future development of anticancer agents.

Also in BMC Cancer this week, researchers at Germany's Martin Luther University Halle-Wittenberg report having found "a significant association between the expression of Piwi-like 2 and 4 mRNAs and the tumor-specific survival of soft tissue sarcoma patients." Measuring expression of those Piwi-like mRNAs in 125 soft tissue sarcoma samples using qPCR, later applying statistical tests to correlate expression readouts with patient survival, the researchers also identified a connection between sex and the impact of Piwi-like mRNA expression on soft tissue sarcoma patients' prognosis, they write.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.