This Week in BMC Cancer | GenomeWeb

This Week in BMC Cancer

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In BMC Cancer this week, researchers in Taiwan say that both isoforms of the Tazarotene-induced gene 1 tumor supressor gene supress cell growth in human colon cancer cell lines. Although the B isoform of TIG1 is known to inhibit growth and invasion of cancer cells, not much is known about the A isoform, the researchers write. In this study, the team found that both TGI1 isoforms are expressed at high levels in normal prostate tissue, and are downregulated in colon cancer cell lines.

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In Science this week: genetic target for urothelial bladder cancer treatment, and more.

At the Conversation, the University of Oxford's Michael Macklay writes that learning genetic risk of disease is a personal decision.

Two dozen scientific organizations have endorsed the March for Science, according to ScienceInsider.

Researchers in Japan describe a chimpanzee with a chromosomal abnormality similar to human Down syndrome, Mashable reports.