Skip to main content
Premium Trial:

Request an Annual Quote

Wayne State, SickKids to Team on OCD Gene Studies

NEW YORK (GenomeWeb News) – Wayne State University, the University of Toronto/Hospital for Sick Children (SickKids), and the Children's Hospital of Michigan an will use a grant from the National Institute of Mental Health in a collaboration that will involve genetics and bioimaging to study genes linked to obsessive-compulsive disorder, WSU said on Monday.

Led by WSU, the "Brain Chemistry and Genetics in Pediatric OCD" project will use the $2.7 million grant to study the role of glutamate in OCD.

"Glutamate is the brain's light switch which helps turn serotonin and other chemicals off and on," David Rosenberg, a professor of psychiatry in WSU's School of Medicine, said in a statement. "Our research has shown that glutamate abnormalities in OCD have significant treatment implications. This new study will further our research by combining imaging and genetics, something never assessed in OCD patients."

Under the collaboration, University of Toronto and SickKids Professor Paul Arnold will lead genetics studies, and the imaging studies will be conducted by Wayne State researchers at the Children's Hospital of Michigan.

"[W]e hope that combining the two powerful techniques of neuroimaging and genetics will help speed up the discovery of risk genes," Arnold said.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.