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Washington University Geneticist, US Genomics Ink Deal to Develop Linear DNA Analysis

NEW YORK, Feb. 21 - Washington University School of Medicine geneticist and dermatologist Pui-Yan Kwok has arranged a deal with US Genomics to use and develop the company's linear DNA analysis method.


Under this partnership, announced on Wednesday, Kwok will adapt US Genomics' direct linear DNA analysis technology to generate new sequence data and explore and map areas of interest. He will also work to extend the company's technology into other applications in genetics.


The company did not disclose financial details of the arrangement.


Kwok's research is focused on identifying new markers associated with complex genetic traits and diseases, and speeding up discovery of polymorphisms and sequence variations.


His group at Washington University is trying to identify polymorphisms by capturing heteroduplex DNA fragments prior to cloning, and by comparing sequence segments generated by the various efforts in the Human Genome Project to identify significant individual differences.


US Genomics, based in Woburn, Mass., has a core technology that allows for high-speed reading of long strands of DNA. The firm also has a research collaboration with the Wellcome Trust Sanger Institute.

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