Skip to main content
Premium Trial:

Request an Annual Quote

Washington Center to Publicly Release Tool That Determines Number of Arrays Needed for Experiments

WASHINGTON, DC, Aug. 25 (GenomeWeb News) - Children's National Medical Center will post an analysis tool within one month that will enable researchers to determine how many microarrays they will need to run a particular experiment, according to an CNMC official.

 

The free tool, called Power Analysis, will be posted on the center's Public Expression Profiling Resource website, an online expression data depository, according to Eric Hoffman, who heads the CNMC's ResearchCenterfor Genetic Medicine. He disclosed the CNMC's plans at Cambridge Healthtech Institute's Total Microarray Data Analysis and Interpretation conference, held here this week.

 

Hoffman said that there was a need for a tool that would allow researchers involved in clinical trials or exploratory research to "design an ethical experiment" using the appropriate number of samples and "alleviate multiple testing problems" by only running as many arrays as were determined to be necessary.

 

Hoffman said the tool had been developed with fellow CNMC scientist Jinwook Seo and others, and that it would be public domain. A paper is in the works.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.