This story has been updated from a previous version.

BETHESDA, Md., Feb 28 – Health and Human Services Secretary Tommy Thompson said Wednesday that if President George W. Bush remains committed to doubling the NIH budget by 2003 from 1998 levels, he would have to implement a relatively large 18 percent increase next year.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.