NEW YORK, April 18 - Orchid Bioscience said today it will fire 15 percent of its staff, or about 90 people, shift several operations, and shutter a number of facilities outright.

The company said it hopes the restructuring, which is expected to continue through the fall, will help it become profitable by the end of next year.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.